Resources for your practice and your patients

ANNOUNCER:

Once-daily TRELEGY is a prescription medicine used long term to treat chronic obstructive pulmonary disease, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Remember to watch the complete video to see additional safety information.

TEXT ONSCREEN:

Once-daily TRELEGY 100/62.5/25 mcg is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Watch the complete video to see additional safety information.

Important Safety Information

• Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.

• Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.

• Do not use TRELEGY more often than prescribed.

• Do not take TRELEGY with other medicines that contain a long-acting beta₂-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.

Please see additional Important Safety Information on this web page.

Please see full Prescribing Information, including Patient Information, on this web page.

TEXT ONSCREEN: My life with COPD

MIKE:

Once I had COPD I noticed that it took me longer to do stuff, like cutting the grass or, you know, you'd stop, take a break.

TEXT ONSCREEN:

Real patients who were taking TRELEGY at the time of filming and one of their caregivers. GSK paid them for their time and expenses for sharing their unique experiences. Individual results may vary.

MIKE:

It slowed my whole life down.

TEXT ONSCREEN:

Mike

MELISSA:

You know I used to be able to, to jog and do a quick trot around the neighborhood. And you know, wave to all the dogs and the, and the kids that were out and, and have a great time. And then I was slower and slower, and then it was almost a crawl to get around to see everybody. So for a while I actually even eliminated that part of my life, and that wasn't, it wasn't any fun. It wasn’t any fun. I missed it.

TEXT ONSCREEN:

Melissa

RODNEY:

I got to the point where I didn't do much fishing because it was too much of a chore. Woodworking was the same way. I- I- didn't enjoy it anymore because it was too hard.

TEXT ONSCREEN:

Rodney

TEXT ONSCREEN: Wanting more

MIKE:

I've had several flare-ups and I'd be treated with steroids and antibiotics, and, it would, it would feel like you were hit with a bad flu stick, is what it felt like. I missed out on several activities when I'd have these flare-ups. With Susan, there were things that she went ahead and did and I just canceled out on.

TEXT ONSCREEN:

A flare-up (or exacerbation) is the worsening of COPD symptoms for several days or weeks that may require steroids, antibiotics, or hospital stays.

MELISSA:

They're hard and it feels like there's an anvil right here and it's very, very difficult to take a deep breath.

MIKE:

I wanted more from a COPD treatment...with TRELEGY it was one medicine that had all the medicines in it I needed.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

MIKE:

I pick up my TRELEGY inhaler and use it once a day.

TEXT ONSCREEN: What 3 in 1 can do

DR. CORBRIDGE:

TRELEGY has two bronchodilators that will help you with the symptoms of COPD…

TEXT ONSCREEN:

Individual results may vary.

DR. CORBRIDGE:

…and the main one there being shortness of breath. And it has that third drug which is that anti-inflammatory,…

TEXT ONSCREEN:

Dr. Corbridge, Pulmonologist

DR. CORBRIDGE:

…which we know is well positioned to prevent those exacerbations that you're at risk for.

TEXT ONSCREEN:

Dr. Corbridge is a physician and was a GSK employee at time of filming.

DR. CORBRIDGE:

And it's conveniently administered. One inhalation per day I think is helping our patients.

TEXT ONSCREEN:

Individual results may vary. TRELEGY won’t replace a rescue inhaler.

SUSAN:

When Mike couldn’t help in the yard it really affected him and he became so apologetic. He always felt so bad and would apologize, “I’m so sorry I can’t help you out there.”

TEXT ONSCREEN:

Individual results may vary.

SUSAN:

And now that he is taking the TRELEGY he is able to get out there.

MIKE:

I’m more content.

SUSAN:

Content is a good word.

MIKE:

Yeah, I’m more content now because I’m not sitting on the sideline watching other people do stuff.

TEXT ONSCREEN:

Individual results may vary.

TEXT ONSCREEN: Want more from a COPD treatment? Ask your doctor if TRELEGY is right for you

ANNOUNCER:

TRELEGY won’t replace a rescue inhaler for sudden breathing problems.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

ANNOUNCER:

Tell your doctor if you have a heart condition or high blood pressure before taking it.

ANNOUNCER:

Do not take TRELEGY more than prescribed. TRELEGY may increase your risk of thrush, pneumonia, and osteoporosis.

TEXT ONSCREEN:

Use TRELEGY only once a day, every day.

ANNOUNCER:

Call your doctor if worsened breathing, chest pain, mouth or tongue swelling, problems urinating, vision changes, or eye pain occur.

TEXT ONSCREEN:

Click here to watch a video on how TRELEGY works

Please see additional Important Safety Information and full Prescribing Information, including Patient Information on this web page.

TRELEGY ELLIPTA was developed in collaboration with INNOVIVA. The shape of the ELLIPTA inhaler is a trademark of GSK. Trademarks owned or licensed by GSK. ©2020 GSK or licensor. FVUVID200021 September 2020. Produced in USA.

Close transcript

ANNOUNCER:

Once-daily TRELEGY is a prescription medicine used long term to treat chronic obstructive pulmonary disease, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Remember to watch the complete video to see additional safety information.

TEXT ONSCREEN:

Once-daily TRELEGY 100/62.5/25 mcg is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Watch the complete video to see additional safety information.

Important Safety Information

• Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.

• Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.

• Do not use TRELEGY more often than prescribed.

• Do not take TRELEGY with other medicines that contain a long-acting beta₂-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.

Please see additional Important Safety Information on this web page.

Please see full Prescribing Information, including Patient Information, on this web page.

TEXT ONSCREEN: How TRELEGY works

DR. CORBRIDGE:

TRELEGY really is a first of its kind…

TEXT ONSCREEN:

Dr. Corbridge, Pulmonologist

DR. CORBRIDGE:

…that provides three of the important medications that we currently know work in patients with COPD.

TEXT ONSCREEN:

Dr. Corbridge is a physician and was a GSK employee at time of filming.

DR. CORBRIDGE:

So it has two bronchodilators.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

DR. CORBRIDGE:

They're called LAMAs and LABAs. These will open up the airway to improve symptoms, and the main one there being shortness of breath. And it has that anti-inflammatory medication…

TEXT ONSCREEN:

LABA opens your airways. LAMA keeps them open. ICS reduces inflammation.

DR. CORBRIDGE:

…that really is positioned to cut down on risk for exacerbations, and it's conveniently administered. One puff, once a day.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

TEXT ONSCREEN: Finding out about TRELEGY

MIKE:

Well, I went to the doctor and I actually felt like I was losing ground. And I had been reading a magazine, and there was another medicine to go along with what I was taking.

TEXT ONSCREEN:

Real patients who were taking TRELEGY at the time of filming and one of their caregivers. GSK paid them for their time and expenses for sharing their unique experiences. Individual results may vary.

MIKE:

And I asked her, I said, “Would this help me?” And she said, “You know we can try that,” and she actually walked out of the room and came back in. She said, “You know what, wait a minute, let's try you on TRELEGY."

TEXT ONSCREEN:

Mike

MELISSA:

I had seen it on television about this drug TRELEGY. When I got to my doctor, I noticed there’s a poster up on his wall with the inhaler...

TEXT ONSCREEN:

Melissa

MELISSA:

...and I said, “Now how about this stuff?” And at the same time, he said to me, “I think I want you to try this,” and we’re both pointing at it. And, I’m so glad he did because I feel better.

TEXT ONSCREEN:

Individual results may vary.

TEXT ONSCREEN: Noticing the results

DIANE:

With the right medication, you can still get out there.

TEXT ONSCREEN:

Diane

Individual results may vary.

DIANE:

I do spend time with my grandkids now. If they want to go to the park, if they want to go somewhere, I can take them.

TEXT ONSCREEN:

Individual results may vary.

RODNEY:

We’ve got plans now more so than ever of traveling a little bit.

TEXT ONSCREEN:

Rodney

Individual results may vary.

MELISSA: Now that I’m on TRELEGY, I’ve noticed a difference in my breathing. Overall, I noticed that I’m feeling like I can go a little bit longer. And for me that’s a good thing. I can maybe dance a little bit longer. That would be great, too.

TEXT ONSCREEN:

Individual results may vary.

TEXT ONSCREEN: Want more from a COPD treatment? Ask your doctor if TRELEGY is right for you

ANNOUNCER:

TRELEGY won’t replace a rescue inhaler for sudden breathing problems.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

ANNOUNCER:

Tell your doctor if you have a heart condition or high blood pressure before taking it.

ANNOUNCER:

Do not take TRELEGY more than prescribed. TRELEGY may increase your risk of thrush, pneumonia, and osteoporosis.

TEXT ONSCREEN:

Use TRELEGY only once a day, every day.

ANNOUNCER:

Call your doctor if worsened breathing, chest pain, mouth or tongue swelling, problems urinating, vision changes, or eye pain occur.

TEXT ONSCREEN:

Click here to watch a video on why TRELEGY might be right for you

Please see additional Important Safety Information and full Prescribing Information, including Patient Information on this web page.

TRELEGY ELLIPTA was developed in collaboration with INNOVIVA. The shape of the ELLIPTA inhaler is a trademark of GSK. Trademarks owned or licensed by GSK. ©2020 GSK or licensor. FVUVID200022 September 2020. Produced in USA.

Close transcript

ANNOUNCER:

Once-daily TRELEGY is a prescription medicine used long term to treat chronic obstructive pulmonary disease, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Remember to watch the complete video to see additional safety information.

TEXT ONSCREEN:

Once-daily TRELEGY 100/62.5/25 mcg is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Watch the complete video to see additional safety information.

Important Safety Information

• Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.

• Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.

• Do not use TRELEGY more often than prescribed.

• Do not take TRELEGY with other medicines that contain a long-acting beta₂-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.

Please see additional Important Safety Information on this web page.

Please see full Prescribing Information, including Patient Information, on this web page.

TEXT ONSCREEN: Daily life may change with TRELEGY

MELISSA:

Now that I've been on TRELEGY for a year, I really think that I've improved. I can take a deeper breath.

TEXT ONSCREEN:

Real patients who were taking TRELEGY at the time of filming and one of their caregivers. GSK paid them for their time and expenses for sharing their unique experiences. Individual results may vary.

MELISSA:

So that helps me with swimming. I'm moving more.

TEXT ONSCREEN:

Melissa

Individual results may vary.

SUSAN:

Mike loves his fishing. He's always loved his fishing. And before, when he would go fishing, sometimes, he would come back and he would be in the bed for a day. The following day, he would be in the bed.

MIKE:

You know, you’d be confined to the bed. It would be so bad that you...

TEXT ONSCREEN:

Mike & Susan

Individual results may vary.

MIKE:

...you'd be back on steroids and back on antibiotics.

TEXT ONSCREEN:

Individual results may vary. TRELEGY won’t replace a rescue inhaler.

SUSAN:

But now he's been able to get out on his boat and go fishing.

TEXT ONSCREEN:

TRELEGY has been proven to reduce flare-ups. Individual results may vary.

DIANE:

The other two medications I took, I had a lot of flare-ups.

TEXT ONSCREEN:

Diane

TRELEGY has been proven to reduce flare-ups.

DIANE:

But now that I'm on TRELEGY I have fewer, so a lot better.

TEXT ONSCREEN:

Individual results may vary.

SUSAN:

Mike's been on TRELEGY for one year now, and I can honestly say he has been on a very, very, stable, even level throughout this past year. And I'm really tickled to death about it.

TEXT ONSCREEN:

Individual results may vary.

TEXT ONSCREEN: Knowing when change is needed

DR. CORBRIDGE:

The perfect patient for triple therapy would be the patient who's symptomatic…

TEXT ONSCREEN:

Dr. Corbridge, Pulmonologist

DR. CORBRIDGE:

…having shortness of breath from COPD, but also…

TEXT ONSCREEN:

Dr. Corbridge is a physician and was a GSK employee at time of filming.

DR. CORBRIDGE:

…is viewed as being at risk for having exacerbations. TRELEGY really is a first of its kind that provides 3 of the important medications that we currently know work in patients with COPD.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

DR. CORBRIDGE:

We know TRELEGY can cut down on exacerbations. It would be great to prevent that.

TEXT ONSCREEN:

Individual results may vary. TRELEGY won’t replace a rescue inhaler.

TEXT ONSCREEN: Change how you live with COPD. Ask your doctor if TRELEGY is right for you

ANNOUNCER:

TRELEGY won’t replace a rescue inhaler for sudden breathing problems.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

ANNOUNCER:

Tell your doctor if you have a heart condition or high blood pressure before taking it.

ANNOUNCER:

Do not take TRELEGY more than prescribed. TRELEGY may increase your risk of thrush, pneumonia, and osteoporosis.

TEXT ONSCREEN:

Use TRELEGY only once a day, every day.

ANNOUNCER:

Call your doctor if worsened breathing, chest pain, mouth or tongue swelling, problems urinating, vision changes, or eye pain occur.

TEXT ONSCREEN:

Click here to watch a video on using TRELEGY

Please see additional Important Safety Information and full Prescribing Information, including Patient Information on this web page.

TRELEGY ELLIPTA was developed in collaboration with INNOVIVA.

The shape of the ELLIPTA inhaler is a trademark of GSK. Trademarks owned or licensed by GSK. ©2020 GSK or licensor. FVUVID200023 September 2020. Produced in USA.

Close transcript

ANNOUNCER:

Once-daily TRELEGY is a prescription medicine used long term to treat chronic obstructive pulmonary disease, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Remember to watch the complete video to see additional safety information.

TEXT ONSCREEN:

Once-daily TRELEGY 100/62.5/25 mcg is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Watch the complete video to see additional safety information.

Important Safety Information

• Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.

• Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.

• Do not use TRELEGY more often than prescribed.

• Do not take TRELEGY with other medicines that contain a long-acting beta₂-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.

Please see additional Important Safety Information on this web page.

Please see full Prescribing Information, including Patient Information, on this web page.

TEXT ONSCREEN: A simpler treatment routine

RODNEY:

TRELEGY, you only take it once a day, where a lot of the other drugs I was taking were twice a day. Some in the mornin', some in the evenin'. Then I'd have to take something midday.

TEXT ONSCREEN:

Real patients who were taking TRELEGY at the time of filming and one of their caregivers. GSK paid them for their time and expenses for sharing their unique experiences. Individual results may vary. TRELEGY won’t replace a rescue inhaler.

RODNEY:

And, you know, bein' active and working…

TEXT ONSCREEN:

Rodney

RODNEY:

TRELEGY you take once in the morning, and that's it.

TEXT ONSCREEN:

Use TRELEGY one time each day, at the same time every day.

TRELEGY won’t replace a rescue inhaler.

RODNEY:

….I mean, it doesn't sound like much, cuttin' it from two a day to one a day, but—

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

MIKE:

Or just one medicine. Havin' the one medicine instead of the two.

TEXT ONSCREEN:

Mike

TRELEGY won’t replace a rescue inhaler.

TEXT ONSCREEN: The impact of TRELEGY

DR. CORBRIDGE:

First things that we hear really have to do with improvement in symptoms.

TEXT ONSCREEN:

Dr. Corbridge, Pulmonologist

DR. CORBRIDGE:

"I just feel better." Kind of, of—often that's just a general sense of feeling, you know less ill.

TEXT ONSCREEN:

Individual results may vary.

DR. CORBRIDGE:

This is maintenance therapy, meaning, you know, it's once a day, one inhalation.

TEXT ONSCREEN:

Dr. Corbridge is a physician and was a GSK employee at time of filming.

TRELEGY won't replace a rescue inhaler.

DR. CORBRIDGE:

It is important to educate patients regarding the need to take TRELEGY as prescribed even if they feel better, so that TRELEGY can continue to help them breathe easier and decrease exacerbation risk.

TEXT ONSCREEN:

Individual results may vary.

TRELEGY won't replace a rescue inhaler.

DR. CORBRIDGE:

You know, you need to take it regularly to get the—the real, palpable benefits of the medication.

TEXT ONSCREEN:

Individual results may vary.

DIANE:

With TRELEGY, it's once a day. The other medications I was on...

TEXT ONSCREEN:

Use TRELEGY one time each day, at the same time every day. TRELEGY won’t replace a rescue inhaler.

DIANE:

I would get up at 3:30 in the mornin’. I would take the first medicine.

TEXT ONSCREEN:

Diane

DIANE:

Then I would have to leave work and come home and do the second medicine. And with TRELEGY, I do it at 3:30 in the mornin', every day, and that's it. I'm done. That's it.

TEXT ONSCREEN:

Use TRELEGY one time each day, at the same time every day.

TRELEGY won’t replace a rescue inhaler.

TEXT ONSCREEN: Are you ready for a simpler treatment routine? Ask your doctor if TRELEGY is right for you

ANNOUNCER:

TRELEGY won’t replace a rescue inhaler for sudden breathing problems.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

ANNOUNCER:

Tell your doctor if you have a heart condition or high blood pressure before taking it.

ANNOUNCER:

Do not take TRELEGY more than prescribed. TRELEGY may increase your risk of thrush, pneumonia, and osteoporosis.

TEXT ONSCREEN:

Use TRELEGY only once a day, every day.

ANNOUNCER:

Call your doctor if worsened breathing, chest pain, mouth or tongue swelling, problems urinating, vision changes, or eye pain occur.

TEXT ONSCREEN:

Click here to watch a video about talking to your doctor

Please see additional Important Safety Information and full Prescribing Information, including Patient Information on this web page.

TRELEGY ELLIPTA was developed in collaboration with INNOVIVA. The shape of the ELLIPTA inhaler is a trademark of GSK. Trademarks owned or licensed by GSK. ©2020 GSK or licensor. FVUVID200024 September 2020. Produced in USA.

Close transcript

ANNOUNCER:

Once-daily TRELEGY is a prescription medicine used long term to treat chronic obstructive pulmonary disease, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Remember to watch the complete video to see additional safety information.

TEXT ONSCREEN:

Once-daily TRELEGY 100/62.5/25 mcg is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Watch the complete video to see additional safety information.

Important Safety Information

• Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.

• Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.

• Do not use TRELEGY more often than prescribed.

• Do not take TRELEGY with other medicines that contain a long-acting beta₂-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.

Please see additional Important Safety Information on this web page.

Please see full Prescribing Information, including Patient Information, on this web page.

MIKE:

I think it’s important for people to ask questions.

TEXT ONSCREEN: Your voice is important

MIKE:

You know, when you go to the doctor, ask, ask, ask, and keep pushing instead of just sitting there listening to what the person tells you.

TEXT ONSCREEN:

Real patients who were taking TRELEGY at the time of filming and one of their caregivers. GSK paid them for their time and expenses for sharing their unique experiences. Individual results may vary.

MELISSA:

I started writing down questions. I had a little notebook.

TEXT ONSCREEN:

Melissa

MIKE:

My wife just goes with me 'cause I don't ask the right questions and I don't come home with the right answers.

MELISSA:

Ah ah, there you go.

TEXT ONSCREEN:

Mike

SUSAN:

I did advocate for Mike that we needed to find out what else was available out there to get him where he's not going up and down so many times.

TEXT ONSCREEN:

Mike & Susan

Individual results may vary.

RODNEY:

I’ve found that you’ve got to be your own advocate, for one thing because your doctor can only treat you for what you tell him. For one thing, how you feel. And I was always one with, well, you know what? My doctor knows best, he’ll give me what he thinks I should have. But you should always...

TEXT ONSCREEN:

Rodney

RODNEY:

...ask him: Is there anything out there that you think could help me better than what I’m taking right now? I never did that…till recently.

TEXT ONSCREEN:

Individual results may vary.

DR. CORBRIDGE:

So we really are looking for a…

TEXT ONSCREEN: How can patients be better partners in treatment?

DR. CORBRIDGE:

…very open exchange—truthful information about where they stand.

TEXT ONSCREEN:

Dr. Corbridge, Pulmonologist

DR. CORBRIDGE:

And also to be able to remember as best you can the life events between clinic visits.

TEXT ONSCREEN:

Dr. Corbridge is a physician and was a GSK employee at time of filming.

DR. CORBRIDGE:

So did you have an exacerbation? Can you remember that, can you report that to me? What were your activities like? What were your symptoms like over that interval? How many rescue inhalations patients are doing. Because that helps me very much to then decide, you know, what next steps are most appropriate.

TEXT ONSCREEN:

A flare-up (or exacerbation) is the worsening of COPD symptoms for several days or weeks that may require steroids, antibiotics, or hospital stays.

TEXT ONSCREEN: Ask your doctor if TRELEGY is right for you

ANNOUNCER:

TRELEGY won’t replace a rescue inhaler for sudden breathing problems.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

ANNOUNCER:

Tell your doctor if you have a heart condition or high blood pressure before taking it.

ANNOUNCER:

Do not take TRELEGY more than prescribed. TRELEGY may increase your risk of thrush, pneumonia, and osteoporosis.

TEXT ONSCREEN:

Use TRELEGY only once a day, every day.

ANNOUNCER:

Call your doctor if worsened breathing, chest pain, mouth or tongue swelling, problems urinating, vision changes, or eye pain occur.

TEXT ONSCREEN:

Click here to watch a video about COPD

Please see additional Important Safety Information and full Prescribing Information, including Patient Information on this web page.

TRELEGY ELLIPTA was developed in collaboration with INNOVIVA. The shape of the ELLIPTA inhaler is a trademark of GSK. Trademarks owned or licensed by GSK. ©2020 GSK or licensor. FVUVID200025 September 2020. Produced in USA.

Close transcript

ANNOUNCER:

Once-daily TRELEGY is a prescription medicine used long term to treat chronic obstructive pulmonary disease, including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Remember to watch the complete video to see additional safety information.

TEXT ONSCREEN:

Once-daily TRELEGY 100/62.5/25 mcg is a prescription medicine used long term to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both, for better breathing and fewer flare-ups. TRELEGY is not used to relieve sudden breathing problems and won’t replace a rescue inhaler. Watch the complete video to see additional safety information.

Important Safety Information

• Do not use TRELEGY to relieve sudden breathing problems. Always have a rescue inhaler with you to treat sudden symptoms.
• Do not use TRELEGY if you have a severe allergy to milk proteins or are allergic to any of the ingredients in TRELEGY. Ask your healthcare provider if you are not sure.
• Do not use TRELEGY more often than prescribed.
• Do not take TRELEGY with other medicines that contain a long-acting beta₂-adrenergic agonist (LABA) or an anticholinergic for any reason. Tell your healthcare provider about all your medical conditions and about all the medicines you take.

Please see additional Important Safety Information on this web page.

Please see full Prescribing Information, including Patient Information, on this web page.

TEXT ONSCREEN: COPD can make you and your loved ones feel overwhelmed

MIKE:

You’re run down, you have no energy.

RODNEY:

I can’t get down on the ground and play with the kids like I used to.

TEXT ONSCREEN:

Real patients who were taking TRELEGY at the time of filming and one of their caregivers. GSK paid them for their time and expenses for sharing their unique experiences. Individual results may vary.

DIANE:

It just kept getting worse. I kept getting … I got depressed. So I kind of stopped doing anything.

TEXT ONSCREEN:

Diane

MIKE:

I was in a full blown panic 'cause I couldn’t catch my breath, and the more I tried, the more I panicked.

TEXT ONSCREEN:

Mike

TRELEGY won’t replace a rescue inhaler.

MELISSA:

He says, "Okay you have it," and he tells you right then how bad it is.

TEXT ONSCREEN:

Melissa

TRELEGY won’t replace a rescue inhaler.

RODNEY:

He says, "Your…your lungs are terrible." And I come out, and told…I told my wife that, and we both had a pretty good cry.

TEXT ONSCREEN:

Rodney

MELISSA:

It’s a, "well, I used to be able to do that."

DIANE:

You’re gonna make me cry.

MELISSA:

Oh no.

DIANE:

Yes.

MELISSA:

'Cause we’re fighters. We’re absolutely fighters.

MIKE:

You can’t change history, but you can change your future.

MELISSA:

Exactly.

TEXT ONSCREEN:

Individual results may vary.

SUSAN:

You wanna go out and do as much research as possible. Find out, really, what is this disease? How are we gonna deal with it? So we started seeking as much information as we possibly could. We started thinking, "What do we have in store for us down the line?"

TEXT ONSCREEN:

Mike & Susan

TEXT ONSCREEN: But you can do something about your COPD

DR. CORBRIDGE:

So there are misconceptions about COPD. In days past, we used to think, or your patients used to think, "There's nothing I can do about this.”

TEXT ONSCREEN:

Dr. Corbridge, Pulmonologist

DR. CORBRIDGE:

We can treat it. And we can make patients feel better.

TEXT ONSCREEN:

Dr. Corbridge is a physician and was a GSK employee at time of filming.

Individual results may vary.

TEXT ONSCREEN: Doing less is not “doing fine”

DR. CORBRIDGE:

We know that patients underreport their symptoms. This is common in COPD. So if you ask a patient in a clinic visit, "How are you?" they often say, "Well, I'm doing fine." That may be because they have stopped doing things, have become more sedentary, stopped climbing stairs, and that mitigates that symptom of breathlessness.

TEXT ONSCREEN: You deserve to feel better

MELISSA:

If you're feeling down at yourself because you think you've brought this on yourself, you’re feeling disgusted, or terrified that “Oh my gosh! I deserve this”– you don't deserve it, nobody deserves it. But now, it's time to get with the program and go see your doctor and get on a medicine.

MIKE:

I know that I made some mistakes in my health earlier, but it's up to you to take control of your life and move on from there. Just because you did this earlier in your life doesn't mean that that defines who you are, you know–you have a chance to do something else now.

TEXT ONSCREEN: The truth is, you can take action. Ask your doctor if TRELEGY is right for you

ANNOUNCER:

TRELEGY won’t replace a rescue inhaler for sudden breathing problems.

TEXT ONSCREEN:

TRELEGY won’t replace a rescue inhaler.

ANNOUNCER:

Tell your doctor if you have a heart condition or high blood pressure before taking it.

ANNOUNCER:

Do not take TRELEGY more than prescribed. TRELEGY may increase your risk of thrush, pneumonia, and osteoporosis.

TEXT ONSCREEN:

Use TRELEGY only once a day, every day.

ANNOUNCER:

Call your doctor if worsened breathing, chest pain, mouth or tongue swelling, problems urinating, vision changes, or eye pain occur.

TEXT ONSCREEN:

Click here to watch a video on how TRELEGY works

Please see additional Important Safety Information and full Prescribing Information, including Patient Information on this web page.

TRELEGY ELLIPTA was developed in collaboration with INNOVIVA. The shape of the ELLIPTA inhaler is a trademark of GSK. Trademarks owned or licensed by GSK. ©2020 GSK or licensor. FVUVID200026 September 2020. Produced in USA.

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TEXT ONSCREEN:

TALES OF BREATHLESSNESS

TEXT ONSCREEN:

A PATIENT’S TALE

The consequences of COPD

VOICEOVER:

I was a builder my whole life.

VOICEOVER:

I loved it.

VOICEOVER:

But I couldn’t wait to retire.

VOICEOVER:

Me and my wife talked about it all the time.

VOICEOVER:

We never traveled much.

VOICEOVER:

So we planned to make up for it by retiring early so I could spend more time with my family.

VOICEOVER:

I took on extra jobs whenever I could…

VOICEOVER:

It was tough on my wife and kids, but I told them it would be worth it.

VOICEOVER:

But despite all the planning, all the dreaming, we never factored in COPD. The breathlessness and tightness in my chest meant I had to start turning down jobs.

VOICEOVER:

I was given a maintenance inhaler by my doctor. But even taking that twice a day didn’t stop me from having a flare-up when I was 60.

VOICEOVER:

I think it’s called an exacerbation. After that my health took a big hit…so I did retire early. But not the way I’d planned.

TEXT ONSCREEN:

Who might be at risk of exacerbation?

Your patients with COPD may be at risk of exacerbation if they:

·      Have had at least 1 exacerbation in the prior 12 months

·      Are on maintenance therapy but have increased symptoms

·      Experience worsening lung function

·      Have had a recent hospitalization due to an exacerbation

TEXT ONSCREEN:

Consequences of exacerbations can be significant

·      Associated with increased risk of mortality

·      Most common reason for COPD-related hospitalizations

·      Major contributor to economic burden

·      Decreased health-related quality of life

Just 1 moderate to severe exacerbation can lead to a significant decline in lung function

VOICEOVER:

That was a couple of years ago…I don’t leave the house much now.

VOICEOVER:

The hardest part is how my COPD affects my wife.

VOICEOVER:

She works so hard and has to take care of everything.

VOICEOVER:

And all those travel plans? We don’t talk about them anymore.

VOICEOVER:

This isn’t the life we dreamed of. It’s certainly not the life she deserves.

TEXT ONSCREEN:

It doesn’t have to be this way for your COPD patients.

TEXT ONSCREEN:

Even if your patients don’t raise issues about their COPD, they may need your help to identify poor symptom control and possible undertreatment with their current maintenance therapy.

TEXT ONSCREEN:

You could make a difference before it’s too late.

Trademarks are owned by or licensed to the GSK group of companies.

[GSK logo]

©2021 GSK or licensor. FVUVID210024

October 2021 Produced in USA.

TEXT ONSCREEN:

References

1. Hurst JR, et al. N Engl J Med. 2010;363(12):1128-1138.

2. Müllerova H, et al. Chest. 2015;147(4):999-1007.

3. Lindenauer PK, et al. Am J Respir Crit Care Med. 2018;197(8):1009-1017.

4. Mapel DW, et al. Value in Health. 2008;11(4):628-636.

5. GOLD. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2021 report. www.goldcopd.org

6. Yu AP, et al. J Med Econ. 2011;14(3):315-323.

7. Seemungal TAR, et al. Am J Respir Crit Care Med. 1998;157(5):1418-1422.

8. Halpin DMG, et al. Respir Med. 2017;128:85-91.

Definitions

COPD=chronic obstructive pulmonary disease; GOLD=Global Initiative for Chronic Obstructive Lung Disease.

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TEXT ONSCREEN:

TALES OF BREATHLESSNESS

TEXT ONSCREEN:

A PHYSICIAN’S TALE

Identifying COPD patients who remain symptomatic despite maintenance treatment with an ICS/LABA

VOICEOVER:

There are people you meet throughout your career who you never forget. For me, it was James–a patient I diagnosed with COPD some time ago.

VOICEOVER:

Whenever I asked how he was doing on his maintenance medication, he said he was feeling fine.

VOICEOVER:

So it came as a shock when James’s wife wanted to come to one his appointments and told me the full impact COPD was having on their lives.

VOICEOVER:

His wife told me James was coughing and wheezing more and experiencing shortness of breath…

VOICEOVER:

…which made climbing stairs and carrying out daily tasks more difficult.

VOICEOVER:

His symptoms were also causing him to wake during the night…

VOICEOVER:

…and leaving him nervous about leaving the house.

VOICEOVER:

That’s when I realized that James hadn’t been giving me the full picture.

VOICEOVER:

And if I didn’t reassess his maintenance treatment, his symptoms could continue to worsen and lead to an exacerbation.

TEXT ONSCREEN:

Even when they were prescribed FP/SAL, an ICS/LABA, nearly 90% of patients with COPD had a high symptom burden (CAT≥10)*

*Based on data from an observational claims-linked survey of Medicare Advantage enrollees ≥65 years of age who had been prescribed FP/ SAL in the prior 6 months (n=397).

Study Limitations: A claim for a prescription does not necessarily mean the medication was taken as prescribed. Diagnosis codes on medical claims do not conclusively demonstrate presence of disease. Findings may not be generalizable to uninsured or younger patient populations.

TEXT ONSCREEN:

COPD exacerbations may be underreported by patients, which could lead to undertreatment of COPD.

TEXT ONSCREEN:

Up to half of COPD exacerbations may go unreported,* making it harder to assess a patient’s future exacerbation risk.

*Based on data from a 12-month study of patients with moderate to severe COPD (N=70).

An exacerbation was defined as worsening symptoms, compatible with a reported exacerbation, for at least 2 consecutive days.

TEXT ONSCREEN:

There are some things that can help you see the full picture of their COPD.

VOICEOVER:

Since then, I’ve changed my  approach. To find out how COPD is really impacting patients, I have specific questions I make sure I ask during appointments that require more than just ‘yes’, ‘no’, or ‘ok’ responses.

TEXT ONSCREEN:

How do your symptoms affect your daily activities?

How often do your symptoms cause you to wake up at night?

How do your symptoms affect how far you can walk or how many stairs you can climb?

VOICEOVER:

Some patients don’t always notice their symptoms are getting worse as it can happen gradually, so I ask them to keep a note of them.

VOICEOVER:

But even then…

VOICEOVER:

…it’s not always easy.

VOICEOVER:

James has helped me to see the importance of COPD management…

VOICEOVER:

…and timely optimization of treatment.

VOICEOVER:

And to always try to get the full picture of how COPD is impacting my patients and their loved ones.

VOICEOVER:

And to never just accept ‘I’m fine’.

TEXT ONSCREEN:

Even if some of your patients tell you that they’re doing ‘okay’ on an ICS/LABA, it’s important to investigate deeper. You might not be getting the complete picture of how COPD has impacted their lives.

Trademarks are owned by or licensed to the GSK group of companies.

[GSK logo]

©2021 GSK or licensor. FVUVID210025

October 2021 Produced in USA.

TEXT ONSCREEN:

References

1. Moretz C, et al. Int J Chron Obstruct Pulmon Dis. 2020;15:2715-2725. Supplementary Table 1.

2. Pavord ID, et al. Int J Chron Obstruct Pulmon Dis. 2016;11:21-30.

3. GOLD. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2021 report. www.goldcopd.org

4. Seemungal TAR, et al. Am J Respir Crit Care Med. 1998;157(5):1418-1422.

Definitions

CAT=COPD Assessment Test; COPD=chronic obstructive pulmonary disease; FP=fluticasone propionate; GOLD=Global Initiative for Chronic Obstructive Lung Disease; ICS=inhaled corticosteroid; LABA=long-acting beta₂-adrenergic agonist; SAL=salmeterol.

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TEXT ONSCREEN:

TALES OF BREATHLESSNESS

TEXT ONSCREEN:

A LOVED ONE’S TALE

A Grandmother’s Story Through Her Grandson’s Eyes

VOICEOVER:

My grandma is my biggest fan.

VOICEOVER:

She has been coming to every game for as long as I can remember.

VOICEOVER:

Come rain or shine,

VOICEOVER:

...she’s always on the sidelines cheering me, but mainly yelling out ‘tactics’ and ‘advice’.

VOICEOVER:

Honestly, she’s more vocal than our coach. [Slight laugh]

VOICEOVER:

But last season, that changed.

VOICEOVER:

My grandma has had COPD for a while, and she had been taking a maintenance inhaler twice a day.

VOICEOVER:

But she started coughing all the time and missing a lot of my games.

VOICEOVER:

One day she was so bad, she couldn’t walk more than a few steps before stopping to catch her breath. I knew she needed to get help.

TEXT ONSCREEN:

Even when they were prescribed FP/SAL, an ICS/LABA, nearly 90% of patients with COPD had a high symptom burden (CAT≥10)*

*Based on data from an observational claims-linked survey of Medicare Advantage enrollees ≥65 years of age who had been prescribed FP/ SAL in the prior 6 months (n=397).

Study Limitations: A claim for a prescription does not necessarily mean the medication was taken as prescribed. Diagnosis codes on medical claims do not conclusively demonstrate presence of disease. Findings may not be generalizable to uninsured or younger patient populations.

VOICEOVER:

It was a hard conversation to have with grandma, but I think she just needed the encouragement and support to go see her doctor again.

VOICEOVER:

At her appointment, the doctor asked grandma lots of questions about how her COPD was impacting her life. And how had her daily routine changed since he last saw her. She told him about her breathing difficulties and how she was finding it more challenging to come to my games.

VOICEOVER:

When he asked if her COPD was worrying her, she said her symptoms were keeping her from going out and she was scared she wouldn’t be able to care for me the same way. She was also worried she might not be able to take care of herself eventually. I had no idea she was so worried.

TEXT ONSCREEN:

How do your symptoms affect your daily activities?

How often do your symptoms cause you to wake up at night?

How do your symptoms affect how far you can walk or how many stairs you can climb?

VOICEOVER:

The doctor mentioned a few things that could help. Importantly, he recommended an increase in her treatment so he gave her a different inhaler.

TEXT ONSCREEN:

The 2021 GOLD Report supports escalation to triple therapy for patients with COPD who continue to experience persistent breathlessness or exacerbations on an ICS/LABA.

TEXT ONSCREEN:

If you have patients with COPD who remain symptomatic, it may be time to consider triple therapy.

Trademarks are owned by or licensed to the GSK group of companies.

[GSK logo]

©2021 GSK or licensor. FVUVID210026

October 2021 Produced in USA.

TEXT ONSCREEN:

References

1. Moretz C, et al. Int J Chron Obstruct Pulmon Dis. 2020;15:2715-2725. Supplementary Table 1.

2. GOLD. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2021 report. www.goldcopd.org

Definitions

CAT=COPD Assessment Test; COPD=chronic obstructive pulmonary disease; FP=fluticasone propionate; GOLD=Global Initiative for Chronic Obstructive Lung Disease; ICS=inhaled corticosteroid; LABA=long-acting beta₂-adrenergic agonist; SAL=salmeterol.

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